Postdoctoral Researcher - Pathology

UHN is Canada's #1 hospital and the world's #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

UHN's vision is to build A Healthier World and it's only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

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Union: Non-Union
Site: Princess Margaret Research Institute
Department: Research, Notta Lab
Reports to: Principal Investigator
Work Model: On-Site
Grade: V0:90
Hours: 37.5 hours per week
Salary: $65,000 - $70,000 annually (To commensurate with experience and consistent with UHN compensation policy)
Shifts: Day
Status: Temporary Full-Time (1 year)
Closing Date: March 31, 2025

Position Summary
The Notta laboratory is located at the Princess Margaret Cancer Centre (Toronto, Canada) and is associated with the Medical Biophysics program at the University of Toronto. Our research program is focussed on pancreatic cancer, one of the most aggressive tumour types in oncology. Broadly, our laboratory is interested in several aspects of the disease such as its cellular origins, mechanisms of drug resistance, and tumour evolution. Our laboratory is also part of the Pancreatic Cancer Translational Initiative (PanCuRx) at the Ontario Institute for Cancer Research. The PanCuRx Program is a translational research initiative that aims to significantly improve the lives of patients with pancreatic adenocarcinoma by generating new knowledge about genetic and biologic subsets of disease, mechanisms of tumorigenesis, and unique treatment options.

The Notta Lab is seeking talented individuals to join our team in cutting-edge research on pancreatic cancer. Our projects focus on analyzing primary samples and using both in vitro and in vivo models, such as patient-derived organoids and xenografts. We apply molecular profiling (genomics and transcriptomics) along with histological analysis to explore the mechanisms of pancreatic cancer development.

We welcome applications from trainees with a strong background in histopathology, with experience in either clinical or laboratory settings. The successful candidate will be working under the direct supervision of a Scientific Associate to perform and coordinate pathology-related tasks.

Additional information about the Notta Lab can be found at:
Website: https://www.nottalab.com/
Twitter: @LabNotta

Duties

• Project management
• Coordination of Laser Capture Microdissection project
• Histopathological review of Pancreatic Cancer slides
• Cytomorphological classification of Pancreatic Cancer organoids models
• Histopathological classification of Pancreatic Cancer derived xenograft models
• Coordination the Notta Lab Slide Repository

• An MD with board certification in pathology is required.
• Applicants should have a manuscript in preparation or a publication record at the time of application.
• Experience in pancreatic or gastrointestinal cancer research is preferred.
• While not required, experience with Laser Microdissection (LCM) is a plus.
• Familiarity with digital annotation software (e.g., Qupath) is encouraged.
• Knowledge with Xenograft mouse models is preferred.

Why join UHN?

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/)
• Close access to Transit and UHN shuttle service
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

All applications must be submitted before the posting close date.

UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.