Research Technician ll

The University Health Network, where "above all else the needs of patients come first",
encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute and the Michener Institute of Education. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of ground breaking firsts and a purpose of "Transforming lives and communities through excellence in care, discovery and learning", the University Health Network (UHN),Canada's largest research teaching hospital, brings together over 16,000 employees, more than1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

Union: Non-Union
Site: Princess Margaret Cancer Centre
Department: Princess Margaret Research Institute
Reports to: Sr Scientist
Work Model: On-site
Grade: B0:05
Hours: 37.5 hours per week
Salary: $29.24 - $36.55 per hour: To commensurate with experience and consistent with UHN compensation policy
Shift: Monday - Friday
Status: Temporary Full-Time (1 year contract)
Closing Date: October 15, 2024

Position Summary:

Working under the direction of the Principal Investigator and senior lab staff, the Research Technician II will carry out a range of laboratory techniques to develop novel biomarkers and treatments for head and neck squamous cell carcinoma patients.

Duties

• Generating patient-derived xenograft (PDX) models in mice
• Assessing novel treatment strategies in PDX models
• Evaluating molecular markers in patient tumor tissues
• Tissue culture of a range of cell types/cancer cell lines
• Basic molecular biology techniques such as RNA extractions, qRT-PCR, Western blots, etc.
• Immunostaining of tumor tissues (immunihistochemistry or immunofluorescence)
• Maintenance of organized and detailed lab notes
• Data analysis (e.g. graphing data)

• At minimum, Bachelor of Science degree in Biology, Biochemistry, or similar field, required
• At minimum, three (3) years related and experience in basic techniques such as cell culture, PCR, gel electrophoresis, Western blots, required
• Previous experience with handling laboratory mice, required
• Advanced mouse techniques such as surgical procedures, preferred
• Additional laboratory techniques such as immunohistochemistry, immunofluorescence, confocal microscopy, preferred
• Flow cytometry experience, preferred
• Biostatistical data analysis and/or analysis of high throughput data such as RNAseq, preferred

Why join UHN?

In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/)
• Close access to Transit and UHN shuttle service
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

All applications must be submitted before the posting close date.

UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.